Medication reference
Urea 40.5 Cream
TOPICAL
Urea 40.5 Cream. INDICATIONS & USAGE For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local

Brand names
Evara
Active ingredients
UREA
Indications
INDICATIONS & USAGE For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eshar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis palmaris, keratoderma, corns and calluses, as well as damaged, ingrown and devitalized nails.
Dosage
DOSAGE AND ADMINISTRATION Apply Evara to affected skin twice per day, or as directed by your physician. Rub in until completely absorbed. Apply to diseased or damaged nail(s) twice per day, or as directed by a physician.
Warnings
WARNINGS Avoid contact with eyes, lips and mucous membranes.
Contraindications
CONTRAINDICATIONS This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.
Adverse reactions
ADVERSE REACTIONS: Discontinue use and consult a physician if redness or irritation occurs.
NDC examples
85477-308
Treats these conditions
Source: openFDA + RxNorm · 2026
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