C21.8

Billable

Malignant neoplasm of overlapping sites of rectum, anus and anal canal

C21.8 is the ICD-10-CM code for Malignant neoplasm of overlapping sites of rectum, anus and anal canal. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
C00-D49
Parent
C21
Edition
FY2026

C00-D49 Neoplasms

What this means — in plain language

MedlinePlus · NIH

What is anal cancer? Your anus is the opening at the end of your large intestine. It is where stool (poop) leaves your body. The anus is formed partly from your outer layers of skin and partly from your intestine. Anal cancer is a type of cancer that forms in the tissues of your anus. Who is more likely to develop anal cancer? Anyone can get anal cancer, but you are more likely to develop it if you: You have an…

Read more about Anal Cancer at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Includes

  • Malignant neoplasm of anorectal junction
  • Malignant neoplasm of anorectum
  • Primary malignant neoplasm of two or more contiguous sites of rectum, anus and anal canal

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Frequently asked questions

What is ICD-10 code C21.8?
C21.8 is the ICD-10-CM code for "Malignant neoplasm of overlapping sites of rectum, anus and anal canal". It falls under C00-D49 Neoplasms.
Is C21.8 a billable code?
Yes — C21.8 is a billable, specific ICD-10-CM code valid for reimbursement.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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