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D21

Non-billable

Other benign neoplasms of connective and other soft tissue

D21 is the ICD-10-CM code for Other benign neoplasms of connective and other soft tissue. It is a non-billable category code — use a more specific child code such as D21.0 for billing.

Status
Header (non-billable)
Chapter
C00-D49
Subcodes
8
Edition
FY2026

C00-D49 Neoplasms

What this means — in plain language

MedlinePlus · NIH

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain. Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them.…

Read more about Benign Tumors at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Includes

  • •benign neoplasm of blood vessel
  • •benign neoplasm of bursa
  • •benign neoplasm of cartilage
  • •benign neoplasm of fascia
  • •benign neoplasm of fat
  • •benign neoplasm of ligament, except uterine
  • •benign neoplasm of lymphatic channel
  • •benign neoplasm of muscle
  • •benign neoplasm of synovia
  • •benign neoplasm of tendon (sheath)
  • •benign stromal tumors

Excludes1 — not coded here

  • •benign neoplasm of articular cartilage (D16.-)
  • •benign neoplasm of cartilage of larynx (D14.1)
  • •benign neoplasm of cartilage of nose (D14.0)
  • •benign neoplasm of connective tissue of breast (D24.-)
  • •benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • •benign neoplasm of peritoneum (D20.1)
  • •benign neoplasm of retroperitoneum (D20.0)
  • •benign neoplasm of uterine ligament, any (D28.2)
  • •benign neoplasm of vascular tissue (D18.-)
  • •hemangioma (D18.0-)
  • •lipomatous neoplasm (D17.-)
  • •lymphangioma (D18.1)
  • •uterine leiomyoma (D25.-)

Conditions mapped to this code

MedlinePlus · NIH
Benign Tumors

Plain-language health-topic references grounded in MedlinePlus (NIH/NLM).

Frequently asked questions

What is ICD-10 code D21?
D21 is the ICD-10-CM code for "Other benign neoplasms of connective and other soft tissue". It falls under C00-D49 Neoplasms.
Is D21 a billable code?
No — D21 is a non-billable header code. Use a more specific child code (such as D21.0) for billing.
What are the subcodes of D21?
D21 has 8 more specific child codes, including D21.0, D21.1, D21.2.
What is excluded from D21?
Excludes1 (not coded here): benign neoplasm of articular cartilage (D16.-); benign neoplasm of cartilage of larynx (D14.1); benign neoplasm of cartilage of nose (D14.0); benign neoplasm of connective tissue of breast (D24.-).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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