E21

Non-billable

Hyperparathyroidism and other disorders of parathyroid gland

E21 is the ICD-10-CM code for Hyperparathyroidism and other disorders of parathyroid gland. It is a non-billable category code — use a more specific child code such as E21.0 for billing.

Status
Header (non-billable)
Chapter
E00-E89
Subcodes
6
Edition
FY2026

E00-E89 Endocrine, nutritional and metabolic diseases

What this means — in plain language

MedlinePlus · NIH

Most people have four pea-sized glands, called parathyroid glands, on the thyroid gland in the neck. Though their names are similar, the thyroid and parathyroid glands are completely different. The parathyroid glands make parathyroid hormone (PTH), which helps your body keep the right balance of calcium and phosphorous. If your parathyroid glands make too much or too little hormone, it disrupts this balance. If they…

Read more about Parathyroid Disorders at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Excludes1 — not coded here

  • adult osteomalacia (M83.-)
  • ectopic hyperparathyroidism (E34.2)
  • hungry bone syndrome (E83.81)
  • infantile and juvenile osteomalacia (E55.0)

Excludes2 — not included here

  • familial hypocalciuric hypercalcemia (E83.52)

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Frequently asked questions

What is ICD-10 code E21?
E21 is the ICD-10-CM code for "Hyperparathyroidism and other disorders of parathyroid gland". It falls under E00-E89 Endocrine, nutritional and metabolic diseases.
Is E21 a billable code?
No — E21 is a non-billable header code. Use a more specific child code (such as E21.0) for billing.
What are the subcodes of E21?
E21 has 6 more specific child codes, including E21.0, E21.1, E21.2.
What is excluded from E21?
Excludes1 (not coded here): adult osteomalacia (M83.-); ectopic hyperparathyroidism (E34.2); hungry bone syndrome (E83.81); infantile and juvenile osteomalacia (E55.0).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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