E28.3
Non-billablePrimary ovarian failure
E28.3 is the ICD-10-CM code for Primary ovarian failure. It is a non-billable category code — use a more specific child code such as E28.31 for billing.
E00-E89 Endocrine, nutritional and metabolic diseases
What this means — in plain language
MedlinePlus · NIHWhat is primary ovarian insufficiency (POI)? Primary ovarian insufficiency (POI) happens when your ovaries stop working normally before you are 40. As you get older, fertility naturally decreases. This usually starts around age 40 or later. Menstrual periods may also become irregular as you transition to menopause . If you have POI, these changes happen earlier, before age 40. Sometimes POI can start as early as the…
Read more about Primary Ovarian Insufficiency at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Medications indicated for this condition
FDA labelingDrugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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