E88.81

Non-billable

Metabolic syndrome and other insulin resistance

E88.81 is the ICD-10-CM code for Metabolic syndrome and other insulin resistance. It is a non-billable category code — use a more specific child code such as E88.810 for billing.

Status
Header (non-billable)
Chapter
E00-E89
Parent
E88.8
Subcodes
4
Edition
FY2026

E00-E89 Endocrine, nutritional and metabolic diseases

What this means — in plain language

MedlinePlus · NIH

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat. A metabolic disorder occurs when abnormal…

Read more about Metabolic Disorders at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Use additional code

  • codes for associated manifestations, such as:
  • obesity (E66.-)

Frequently asked questions

What is ICD-10 code E88.81?
E88.81 is the ICD-10-CM code for "Metabolic syndrome and other insulin resistance". It falls under E00-E89 Endocrine, nutritional and metabolic diseases.
Is E88.81 a billable code?
No — E88.81 is a non-billable header code. Use a more specific child code (such as E88.810) for billing.
What are the subcodes of E88.81?
E88.81 has 4 more specific child codes, including E88.810, E88.811, E88.818.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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