F43
Non-billableReaction to severe stress, and adjustment disorders
F43 is the ICD-10-CM code for Reaction to severe stress, and adjustment disorders. It is a non-billable category code — use a more specific child code such as F43.0 for billing.
- Status
- Header (non-billable)
- Chapter
- F01-F99
- Subcodes
- 5
- Edition
- FY2026
F01-F99 Mental, Behavioral and Neurodevelopmental disorders
This category differs from others in that it includes disorders identifiable on the basis of not only symptoms and course but also the existence of one or other of two causative influences: an exceptionally stressful life event producing an acute stress reaction, or a significant life change leading to continued unpleasant circumstances that result in an adjustment disorder. Although less severe psychosocial stress ("life events") may precipitate the onset or contribute to the presentation of a very wide range of disorders classified elsewhere in this chapter, its etiological importance is not always clear and in each case will be found to depend on individual, often idiosyncratic, vulnerability, i.e. the life events are neither necessary nor sufficient to explain the occurrence and form of the disorder. In contrast, the disorders brought together here are thought to arise always as a direct consequence of acute severe stress or continued trauma. The stressful events or the continuing unpleasant circumstances are the primary and overriding causal factor and the disorder would not have occurred without their impact. The disorders in this section can thus be regarded as maladaptive responses to severe or continued stress, in that they interfere with successful coping mechanisms and therefore lead to problems of social functioning.
What this means — in plain language
MedlinePlus · NIHWhat is stress? Stress is how your brain and body respond to a challenge or demand. When you are stressed, your body releases certain hormones . Hormones are chemicals that travel in your bloodstream and control how different parts of your body work. The hormones that are released when you are stressed make you alert and ready to act. They can raise your blood pressure, heart rate, and blood glucose (blood sugar)…
Read more about Stress at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Medications indicated for this condition
FDA labeling- Sertraline›
- Apil Mel, Baptisia, Baryta Carb, Hamamelis, Kali Brom, Kali Phos, Lachesis, Lilium, Petroleum, Phosphoricum Ac, Spigelia Anth, Sulphur, Veratrum VirStandardized Insect Venom Allergenic Extract [EPC]›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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