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R53

Non-billable

Malaise and fatigue

R53 is the ICD-10-CM code for Malaise and fatigue. It is a non-billable category code — use a more specific child code such as R53.0 for billing.

Status
Header (non-billable)
Chapter
R00-R99
Subcodes
4
Edition
FY2026

R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

What this means — in plain language

MedlinePlus · NIH

What is fatigue? Fatigue is a feeling of weariness, tiredness, or lack of energy. It can interfere with your usual daily activities. Fatigue can be a normal response to physical activity, emotional stress , boredom, or lack of sleep. But sometimes it can be a sign of a mental or physical condition. If you have been feeling tired for weeks, contact your health care provider. They can help you find out what's causing…

Read more about Fatigue at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

No additional coding notes for this code.

Frequently asked questions

What is ICD-10 code R53?
R53 is the ICD-10-CM code for "Malaise and fatigue". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Is R53 a billable code?
No — R53 is a non-billable header code. Use a more specific child code (such as R53.0) for billing.
What are the subcodes of R53?
R53 has 4 more specific child codes, including R53.0, R53.1, R53.2.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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