Z16
Non-billableResistance to antimicrobial drugs
Z16 is the ICD-10-CM code for Resistance to antimicrobial drugs. It is a non-billable category code — use a more specific child code such as Z16.1 for billing.
- Status
- Header (non-billable)
- Chapter
- Z00-Z99
- Subcodes
- 3
- Edition
- FY2026
Z00-Z99 Factors influencing health status and contact with health services
What this means — in plain language
MedlinePlus · NIHWhat are antibiotics? Antibiotics are medicines that treat bacterial infections in humans and animals. They work by killing the bacteria or making it hard for the bacteria to grow and multiply. When used properly, antibiotics can save lives. But there is a growing problem of antibiotic resistance. What is antibiotic resistance? Antibiotic resistance happens when bacteria change and can resist the effects of an…
Read more about Antibiotic Resistance at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Excludes1 — not coded here
Code first
- •the infection
Notes
- •The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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