C43
Non-billableMalignant melanoma of skin
C43 is the ICD-10-CM code for Malignant melanoma of skin. It is a non-billable category code — use a more specific child code such as C43.0 for billing.
- Status
- Header (non-billable)
- Chapter
- C00-D49
- Subcodes
- 10
- Edition
- FY2026
C00-D49 Neoplasms
What this means — in plain language
MedlinePlus · NIHMelanoma is the most serious type of skin cancer . Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or "ugly looking." Thinking of "ABCDE" can help you remember what to watch for: Asymmetry - the shape of one half does not match the other Border - the edges are…
Read more about Melanoma at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Excludes1 — not coded here
- •melanoma in situ (D03.-)
Excludes2 — not included here
Medications indicated for this condition
FDA labeling- Hydroquinone, Homosalate, Octisalate, and Zinc Oxide›
- Hydroquinone, Homosalate, Octisalate, Zinc Oxide›
- AtezolizumabProgrammed Death Receptor-1 Blocking Antibody [EPC]›
- Atezolizumab and Hyaluronidase-tqjsProgrammed Death Receptor-1 Blocking Antibody [EPC]›
- Binimetinib›
- DacarbazineAlkylating Drug [EPC]›
- Encorafenib›
- Herpesvirus 1, Human›
- Hydroquinone, Octisalate and Zinc Oxide›
- Hydroquinone, Titanium Dioxide, and Zinc Oxide›
- IpilimumabCTLA-4-directed Blocking Antibody [EPC]›
- Nivolumab and Hyaluronidase-nvhyEndoglycosidase [EPC]›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Frequently asked questions
- What is ICD-10 code C43?
- C43 is the ICD-10-CM code for "Malignant melanoma of skin". It falls under C00-D49 Neoplasms.
- Is C43 a billable code?
- No — C43 is a non-billable header code. Use a more specific child code (such as C43.0) for billing.
- What is excluded from C43?
- Excludes1 (not coded here): melanoma in situ (D03.-).
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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