D56.0

Billable

Alpha thalassemia

D56.0 is the ICD-10-CM code for Alpha thalassemia. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
D50-D89
Parent
D56
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

What this means — in plain language

MedlinePlus · NIH

Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia . Thalassemias occur most often among people of Italian, Greek, Middle Eastern, Southern Asian, and African descent. Thalassemias can be mild or severe. Some people have no symptoms or mild anemia. The most common…

Read more about Thalassemia at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Includes

  • Alpha thalassemia major
  • Hemoglobin H Constant Spring
  • Hemoglobin H disease
  • Hydrops fetalis due to alpha thalassemia
  • Severe alpha thalassemia
  • Triple gene defect alpha thalassemia

Excludes1 — not coded here

  • alpha thalassemia trait or minor (D56.3)
  • asymptomatic alpha thalassemia (D56.3)
  • hydrops fetalis due to isoimmunization (P56.0)
  • hydrops fetalis not due to immune hemolysis (P83.2)

Use additional code

  • code, if applicable, for hydrops fetalis due to alpha thalassemia (P56.99)

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Conditions mapped to this code

MedlinePlus · NIH

Plain-language health-topic references grounded in MedlinePlus (NIH/NLM).

Frequently asked questions

What is ICD-10 code D56.0?
D56.0 is the ICD-10-CM code for "Alpha thalassemia". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D56.0 a billable code?
Yes — D56.0 is a billable, specific ICD-10-CM code valid for reimbursement.
What is excluded from D56.0?
Excludes1 (not coded here): alpha thalassemia trait or minor (D56.3); asymptomatic alpha thalassemia (D56.3); hydrops fetalis due to isoimmunization (P56.0); hydrops fetalis not due to immune hemolysis (P83.2).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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