D68.5
Non-billablePrimary thrombophilia
D68.5 is the ICD-10-CM code for Primary thrombophilia. It is a non-billable category code — use a more specific child code such as D68.51 for billing.
D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
What this means — in plain language
MedlinePlus · NIHNormally, if you get hurt, your body forms a blood clot to stop the bleeding . For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should. Bleeding disorders can be the result of other diseases, such as severe liver disease or a lack of vitamin K .…
Read more about Bleeding Disorders at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Includes
- •Primary hypercoagulable states
Excludes1 — not coded here
- •antiphospholipid syndrome (D68.61)
- •lupus anticoagulant (D68.62)
- •secondary activated protein C resistance (D68.69)
- •secondary antiphospholipid antibody syndrome (D68.69)
- •secondary lupus anticoagulant with hypercoagulable state (D68.69)
- •secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
- •systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
- •systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
- •thrombotic thrombocytopenic purpura (M31.19)
Medications indicated for this condition
FDA labeling- Desmopressin›
- vitamin K1Vitamin K [EPC]›
- ArgatrobanAnti-coagulant [EPC]›
- ADAMTS13, recombinant›
- Caplacizumab›
- factor X›
- Heparin Sodium in Sodium Chloride›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
- What is ICD-10 code D68.5?
- D68.5 is the ICD-10-CM code for "Primary thrombophilia". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
- Is D68.5 a billable code?
- No — D68.5 is a non-billable header code. Use a more specific child code (such as D68.51) for billing.
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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