D75.81

Billable

Myelofibrosis

D75.81 is the ICD-10-CM code for Myelofibrosis. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
D50-D89
Parent
D75.8
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

What this means — in plain language

MedlinePlus · NIH

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells . The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. With bone marrow disease, there are problems with the stem cells or how they develop: In leukemia , a cancer of the…

Read more about Bone Marrow Diseases at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Includes

  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS

Excludes1 — not coded here

  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)

Code first

  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)

Use additional code

  • code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
  • code for adverse effect, if applicable, to identify drug (T45.1X5)

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Frequently asked questions

What is ICD-10 code D75.81?
D75.81 is the ICD-10-CM code for "Myelofibrosis". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D75.81 a billable code?
Yes — D75.81 is a billable, specific ICD-10-CM code valid for reimbursement.
What is excluded from D75.81?
Excludes1 (not coded here): acute myelofibrosis (C94.4-); idiopathic myelofibrosis (D47.1); leukoerythroblastic anemia (D61.82); myelofibrosis with myeloid metaplasia (D47.4).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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