D81
Non-billableCombined immunodeficiencies
D81 is the ICD-10-CM code for Combined immunodeficiencies. It is a non-billable category code — use a more specific child code such as D81.0 for billing.
- Status
- Header (non-billable)
- Chapter
- D50-D89
- Subcodes
- 10
- Edition
- FY2026
D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
What this means — in plain language
MedlinePlus · NIHWhat is the immune system? Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases. When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the disease by fighting off the germs. What are the…
Read more about Immune System and Disorders at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Excludes1 — not coded here
- •autosomal recessive agammaglobulinemia (Swiss type) (D80.0)
Frequently asked questions
- What is ICD-10 code D81?
- D81 is the ICD-10-CM code for "Combined immunodeficiencies". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
- Is D81 a billable code?
- No — D81 is a non-billable header code. Use a more specific child code (such as D81.0) for billing.
- What is excluded from D81?
- Excludes1 (not coded here): autosomal recessive agammaglobulinemia (Swiss type) (D80.0).
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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