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D89.81

Non-billable

Graft-versus-host disease

D89.81 is the ICD-10-CM code for Graft-versus-host disease. It is a non-billable category code — use a more specific child code such as D89.810 for billing.

Status
Header (non-billable)
Chapter
D50-D89
Parent
D89.8
Subcodes
4
Edition
FY2026

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

What this means — in plain language

MedlinePlus · NIH

What is the immune system? Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases. When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the disease by fighting off the germs. What are the…

Read more about Immune System and Disorders at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Code first

  • •underlying cause, such as:
  • •complications of transplanted organs and tissue (T86.-)
  • •complications of blood transfusion (T80.89)

Use additional code

  • •code to identify associated manifestations, such as:
  • •desquamative dermatitis (L30.8)
  • •diarrhea (R19.7)
  • •elevated bilirubin (R17)
  • •hair loss (L65.9)

Frequently asked questions

What is ICD-10 code D89.81?
D89.81 is the ICD-10-CM code for "Graft-versus-host disease". It falls under D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
Is D89.81 a billable code?
No — D89.81 is a non-billable header code. Use a more specific child code (such as D89.810) for billing.
What are the subcodes of D89.81?
D89.81 has 4 more specific child codes, including D89.810, D89.811, D89.812.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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