G12.21
BillableAmyotrophic lateral sclerosis
G12.21 is the ICD-10-CM code for Amyotrophic lateral sclerosis. It is a billable, specific code valid for reimbursement.
G00-G99 Diseases of the nervous system
What this means — in plain language
MedlinePlus · NIHAmyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice: Trouble walking or running Trouble writing Speech problems Eventually, you…
Read more about Amyotrophic Lateral Sclerosis at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Medications indicated for this condition
FDA labeling- Edaravone›
- RiluzoleBenzothiazole [EPC]›
- Onasemnogene Abeparvovec›
- TofersenAntisense Oligonucleotide [EPC]›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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