R53.81

Billable

Other malaise

R53.81 is the ICD-10-CM code for Other malaise. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
R00-R99
Parent
R53.8
Edition
FY2026

R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

What this means — in plain language

MedlinePlus · NIH

What is fatigue? Fatigue is a feeling of weariness, tiredness, or lack of energy. It can interfere with your usual daily activities. Fatigue can be a normal response to physical activity, emotional stress , boredom, or lack of sleep. But sometimes it can be a sign of a mental or physical condition. If you have been feeling tired for weeks, contact your health care provider. They can help you find out what's causing…

Read more about Fatigue at MedlinePlus ↗

Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.

Includes

  • Chronic debility
  • Debility NOS
  • General physical deterioration
  • Malaise NOS
  • Nervous debility

Excludes1 — not coded here

  • age-related physical debility (R54)

Medications indicated for this condition

FDA labeling

Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.

Frequently asked questions

What is ICD-10 code R53.81?
R53.81 is the ICD-10-CM code for "Other malaise". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Is R53.81 a billable code?
Yes — R53.81 is a billable, specific ICD-10-CM code valid for reimbursement.
What is excluded from R53.81?
Excludes1 (not coded here): age-related physical debility (R54).

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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