T80.5
Non-billableAnaphylactic reaction due to serum
T80.5 is the ICD-10-CM code for Anaphylactic reaction due to serum. It is a non-billable category code — use a more specific child code such as T80.51 for billing.
S00-T88 Injury, poisoning and certain other consequences of external causes
What this means — in plain language
MedlinePlus · NIHAnaphylaxis is a serious allergic reaction . It can begin very quickly, and symptoms may be life-threatening. The most common causes are reactions to foods (especially peanuts), medications , and stinging insects . Other causes include exercise and exposure to latex . Sometimes no cause can be found. It can affect many organs: Skin - itching, hives, redness, swelling Nose - sneezing, stuffy nose, runny nose Mouth -…
Read more about Anaphylaxis at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Includes
- •Allergic shock due to serum
- •Anaphylactic shock due to serum
- •Anaphylactoid reaction due to serum
- •Anaphylaxis due to serum
Excludes1 — not coded here
- •ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- •allergic reaction or shock NOS (T78.2)
- •anaphylactic reaction or shock NOS (T78.2)
- •anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- •other serum reaction (T80.6-)
Medications indicated for this condition
FDA labeling- Betamethasone Sodium Phosphate and Betamethasone Acetate›
- Dexchlorpheniramine›
- 8.4% Sodium Bicarbonate›
- Betamethasone Sodium Phosphate, Betamethasone Acetate, Lidocaine, Povidine Iodine›
- CorticotropinAdrenocorticotropic Hormone [EPC]›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
- What is ICD-10 code T80.5?
- T80.5 is the ICD-10-CM code for "Anaphylactic reaction due to serum". It falls under S00-T88 Injury, poisoning and certain other consequences of external causes.
- Is T80.5 a billable code?
- No — T80.5 is a non-billable header code. Use a more specific child code (such as T80.51) for billing.
- What are the subcodes of T80.5?
- T80.5 has 3 more specific child codes, including T80.51, T80.52, T80.59.
- What is excluded from T80.5?
- Excludes1 (not coded here): ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-); allergic reaction or shock NOS (T78.2); anaphylactic reaction or shock NOS (T78.2); anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6).
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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