R65.10
BillableSystemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
R65.10 is the ICD-10-CM code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction. It is a billable, specific code valid for reimbursement.
R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Includes
- •Systemic inflammatory response syndrome (SIRS) NOS
Medications indicated for this condition
FDA labeling- Epinephrinealpha-Adrenergic Agonist [EPC]›
- TocilizumabInterleukin-6 Receptor Antagonist [EPC]›
- 6% Hetastarch in 0.9% Sodium ChloridePlasma Volume Expander [EPC]›
- albumin human, USP›
- angiotensin IIVasoconstrictor [EPC]›
- Epinephrine in Sodium Chloridealpha-Adrenergic Agonist [EPC]›
- Infant 4.2% Sodium Bicarbonate›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Frequently asked questions
- What is ICD-10 code R65.10?
- R65.10 is the ICD-10-CM code for "Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
- Is R65.10 a billable code?
- Yes — R65.10 is a billable, specific ICD-10-CM code valid for reimbursement.
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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